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CAS

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(3-Amino-pyridin-2-yl)-methanol is a complex organic compound that belongs to the class of chemical compounds known as aminomethylpyridines. It is composed of an amino pyridine ring, which is a derivative of pyridine (a six-membered ring with five carbon atoms and one nitrogen atom) with an amino group attached, and a methanol group. Its specific chemical formula is C6H8N2O, and it has a molar mass of 124.14 g/mol. Handling this chemical complex requires appropriate safety measures due to its potential reactivity.

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  • 52378-63-9 Structure

  • Basic information

    1. Product Name: (3-AMINO-PYRIDIN-2-YL)-METHANOL
    2. Synonyms: 3-aMino-2-PyridineMethanol;2-Pyridinemethanol, 3-amino-;3-AMINO-2-(HYDROXYMETHYL)PYRIDINE;(3-AMINO-PYRIDIN-2-YL)-METHANOL;3-Aminopyridine-2-methanol
    3. CAS NO:52378-63-9
    4. Molecular Formula: C6H8N2O
    5. Molecular Weight: 124.14
    6. EINECS: N/A
    7. Product Categories: pharmacetical
    8. Mol File: 52378-63-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 333.1 °C at 760 mmHg
    3. Flash Point: 155.3 °C
    4. Appearance: /
    5. Density: 1.257 g/cm3
    6. Vapor Pressure: 5.53E-05mmHg at 25°C
    7. Refractive Index: 1.627
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    9. Solubility: N/A
    10. PKA: 13.34±0.10(Predicted)
    11. CAS DataBase Reference: (3-AMINO-PYRIDIN-2-YL)-METHANOL(CAS DataBase Reference)
    12. NIST Chemistry Reference: (3-AMINO-PYRIDIN-2-YL)-METHANOL(52378-63-9)
    13. EPA Substance Registry System: (3-AMINO-PYRIDIN-2-YL)-METHANOL(52378-63-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 52378-63-9(Hazardous Substances Data)

52378-63-9 Usage

Uses

Used in Scientific Research and Development:
(3-Amino-pyridin-2-yl)-methanol is used as a chemical intermediate for the synthesis of other types of compounds, playing a crucial role in the advancement of various scientific research and development projects.
Used in Pharmaceutical Industry:
(3-Amino-pyridin-2-yl)-methanol is used as a building block in the development of new pharmaceutical compounds, contributing to the creation of innovative medications and therapies.
Used in Chemical Synthesis:
(3-Amino-pyridin-2-yl)-methanol is used as a reagent in various chemical synthesis processes, enabling the production of a wide range of chemical products with diverse applications.

Check Digit Verification of cas no

The CAS Registry Mumber 52378-63-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,3,7 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 52378-63:
(7*5)+(6*2)+(5*3)+(4*7)+(3*8)+(2*6)+(1*3)=129
129 % 10 = 9
So 52378-63-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2O/c7-5-2-1-3-8-6(5)4-9/h1-3,9H,4,7H2

52378-63-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (3-aminopyridin-2-yl)methanol

1.2 Other means of identification

Product number -
Other names 2-Pyridinemethanol,3-amino

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52378-63-9 SDS

52378-63-9Relevant articles and documents

Sunlight-Driven Forging of Amide/Ester Bonds from Three Independent Components: An Approach to Carbamates

Zhao, Yating,Huang, Binbin,Yang, Chao,Chen, Qingqing,Xia, Wujiong

supporting information, p. 5572 - 5575 (2016/11/17)

A photoredox catalytic route to carbamates enabled by visible irradiation (or simply sunlight) has been developed. This process leads to a novel approach to the construction of heterocyclic rings wherein the amide or ester motifs of carbamates were assembled from three isolated components. Large-scale experiments were realized by employing continuous flow techniques, and reuse of photocatalyst demonstrated the green and sustainable aspects of this method.

NOVEL COMPOUNDS

-

Page/Page column 71, (2011/04/25)

The present invention discloses novel compounds inhibiting LRRK2 kinase activity, the preparation processes thereof, the compositions containing them, as well as the use in treating diseases characterized by LRRK2 kinase activity, particularly Parkinson's disease and Alzheimer's disease.

CXCR4 chemokine receptor binding comounds

-

Page 10, 43, (2010/02/08)

The present invention relates to compounds that bind to chemokine receptors, and having the formula wherein each A, X, Y, R1, R2 and R3 are substituents. The present invention also relates to methods of using such compounds, such as in treating HIV infection and inflammatory conditions such as rheumatoid arthritis. Furthermore, the present invention relates to methods to elevate progenitor and stem cell counts, as well as methods to elevate white blood cell counts, using such compounds.

UV photoelectron spectroscopy studies of the diazaxylylenes generated from amino(hydroxymethyl)pyridines

Chrostowska,Sotiropoulos,Pfister-Guillouzo,Wojciechowski

, p. 535 - 545 (2007/10/03)

Diazaxylylenes generated by 1,4-elimination of water from amino(hydroxymethyl)pyridines under flash vacuum thermolysis (FVT) conditions can be directly studied by the UV-photoelectron spectroscopy (UV-PES). The elimination of water from these compounds starts at 450°C and is completed at 500-550°C. The interpretation of UV-photoelectron spectra was supported by Density Functional Theory studies.

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