4175-78-4

• 

• Basic information

  1. Product Name: 2,5-DIBROMOTHIAZOLE
  2. Synonyms: 2,5-DIBROMOTHIAZOLE;2,5-Dibromo-1,3-thiazole;2,5-DIBROMOTHIAZOLE 95%;2,5-Dibromothiazole,97%;Thiazole, 2,5-dibroMo-;NSC 222407;2,5-Dibormothiazole;DibromoThiazole
  3. CAS NO:4175-78-4
  4. Molecular Formula: C₃HBr₂NS
  5. Molecular Weight: 242.92
  6. EINECS: 1533716-785-6
  7. Product Categories: Sulphur Derivatives;Heterocyclic Compounds;Thiazoles;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;ThiazolesHeterocyclic Building Blocks;Building Blocks;C3 to C7;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;alkyl bromide
  8. Mol File: 4175-78-4.mol

• Chemical Properties

  1. Melting Point: 45-49 °C(lit.)
  2. Boiling Point: 242.8 °C at 760 mmHg
  3. Flash Point: 110 °C
  4. Appearance: White to brown/Crystalline Powder
  5. Density: 2.324 g/cm³
  6. Vapor Pressure: 0.0518mmHg at 25°C
  7. Refractive Index: 1.649
  8. Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
  9. Solubility: soluble in Methanol
  10. PKA: -0.88±0.10(Predicted)
  11. CAS DataBase Reference: 2,5-DIBROMOTHIAZOLE(CAS DataBase Reference)
  12. NIST Chemistry Reference: 2,5-DIBROMOTHIAZOLE(4175-78-4)
  13. EPA Substance Registry System: 2,5-DIBROMOTHIAZOLE(4175-78-4)

• Safety Data

  1. Hazard Codes: Xi
  2. Statements: 36/37/38
  3. Safety Statements: 26-36
  4. WGK Germany: 3
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 4175-78-4(Hazardous Substances Data)

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4175-78-4 Suppliers

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• 2,5-Dibromothiazole Manufacturer/High quality/Best price/In stock

  Cas No: 4175-78-4

• USD $ 3.0-3.0 / Kilogram

• 1 Kilogram

• 1-100 Metric Ton/Month

• Dayang Chem (Hangzhou) Co.,Ltd.
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• High quality 2,5-Dibromothiazole with high purity

  Cas No: 4175-78-4

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• 1 Kilogram

• 30 Metric Ton/Month

• Simagchem Corporation
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• 2,5-Dibromothiazole

  Cas No: 4175-78-4

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• 10 Milligram

• Amadis Chemical Co., Ltd.
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• 2,5-DIBROMOTHIAZOLE

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• 1 Kilogram

• 10 Metric Ton/Quarter

• HENAN NEW BLUE CHEMICAL CO.,LTD
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• Factory direct supply CAS 4175-78-4 with best quality

  Cas No: 4175-78-4

• USD $ 139.0-210.0 / Kilogram

• 1 Kilogram

• 1000 Kilogram/Day

• Zhuozhou Wenxi import and Export Co., Ltd
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• 4175-78-4 2,5-DIBROMOTHIAZOLE

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• HENAN SUNLAKE ENTERPRISE CORPORATION
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• Shijiazhuang Sdyano Fine Chemical Co., Ltd
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• CAS NO.:4175-78-4

  Cas No: 4175-78-4

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• 10000 Metric Ton/Month

• Henan Wentao Chemical Product Co., Ltd.
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• Xiamen Hisunny Chemical Co.,Ltd
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• 1 Kilogram

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• Shandong Hanjiang Chemical Co., Ltd.
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4175-78-4 Usage

Uses

Used in Material Science:
2,5-Dibromothiazole is used as a building block for its unique chemical properties, which contribute to the development of novel materials with enhanced characteristics.
Used in Pharmaceutical Industry:
2,5-Dibromothiazole is used in the preparation of arylthiazolylpiperidine derivatives and analogs, which are crucial for modulating the production of survival motor neuron (SMN) protein. This application is significant for the development of therapeutic strategies targeting spinal muscular atrophy (SMA) and other related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 4175-78-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,7 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4175-78:
(6*4)+(5*1)+(4*7)+(3*5)+(2*7)+(1*8)=94
94 % 10 = 4
So 4175-78-4 is a valid CAS Registry Number.

InChI:InChI=1/C3HBr2NS/c4-2-1-6-3(5)7-2/h1H

4175-78-4 Well-known Company Product Price

• Brand
• (Code)Product description
• CAS number
• Packaging
• Price
• Detail

• TCI America

• (D3960)  2,5-Dibromothiazole  >97.0%(GC)

• 4175-78-4

• 5g

• 1,420.00CNY

• Detail

• Alfa Aesar

• (H26909)  2,5-Dibromothiazole, 97%   

• 4175-78-4

• 5g

• 1682.0CNY

• Detail

• Alfa Aesar

• (H26909)  2,5-Dibromothiazole, 97%   

• 4175-78-4

• 25g

• 5695.0CNY

• Detail

• Aldrich

• (524182)  2,5-Dibromothiazole  97%

• 4175-78-4

• 524182-5G

• 1,757.34CNY

• Detail

4175-78-4Upstream product

• 288-47-1 1,3-thiazole 

4175-78-4Downstream Products

• 903886-70-4 5-bromo-2-(4-isopropylphenoxy)thiazole 
• 903886-65-7 5-bromo-2-(4-isopropoxy-phenoxy)-thiazole 
• 904961-99-5 5-Bromo-2-(4-isopropylsulfanyl-phenoxy)-thiazole 
• 903886-67-9 [4-(5-bromothiazol-2-yloxy)phenyl]carbamic acid tert-butyl ester 
• 916796-13-9 4-(5-bromo-thiazol-2-yloxy)-benzoic acid ethyl ester 
• 916795-99-8 5-bromo-2-(4-isobutyl-phenoxy)-thiazole 
• 904961-84-8 3-(5-Bromo-thiazol-2-yloxy)-benzoic acid ethyl ester 
• 904961-21-3 4-(5-bromothiazol-2-yloxy)phenol 
• 904961-08-6 3-(5-bromo-thiazol-2-yloxy)-phenol 

4175-78-4Relevant articles and documents

COURSE OF BROMINATION OF THIAZOLE AND 2-METHYLTHIAZOLE

Gol'dfarb, Ya. L.,Gromova, G. P.,Belen'kii, L. I.

, p. 663 - 666 (1986)

Bromination of thiazole by bromine in the presence of aluminium chloride in neutral solvent or without solvent takes place at the 2-position.Such an orientation contradicts the traditional addition-cleavage mechanism, and agrees with the ylid mechanism of electrophilic substitution. 2-Methylthiazole brominates at the 5-position, and the reaction is impeded in the presence of aluminium chloride; this is due to heterocycle deactivation by complexation with the Lewis acid at the nitrogen atom.

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