32896-90-5Relevant articles and documents
Hilbert-Johnson reaction under high pressure: A facile preparation of 2-pyridones
Matsumoto, Kiyoshi,Ikemi, Yukio,Suda, Machiko,Iida, Hirokazu,Hamana, Hiroshi
, p. 187 - 190 (2007)
For the first time, a facile synthesis of 2-pyridones utilizing a classical Hilbert-Johnson reaction of 2-methoxypyridines with haloalkanes under high pressure has been achieved. The reactions were sensitive to steric hindrance of haloalkanes.
Kinetic assessment of N-methyl-2-methoxypyridinium species as phosphonate anion methylating agents
Topczewski, Joseph J.,Quinn, Daniel M.
supporting information, p. 1084 - 1087 (2013/04/10)
Organophosphate nerve agents and pesticides are potent inhibitors of acetylcholinesterase (AChE). Although oxime nucleophiles can reactivate the AChE-phosphyl adduct, the adduct undergoes a reaction called aging. No compounds have been described that reactivate the aged-AChE adduct. A family of 2-methoxypyridinium species which reverse aging in a model system is presented. A kinetic study of this system, which includes an SAR analysis, demonstrates that the reaction is highly tunable based on the ring substituents.
NITRATION OF AROMATIC HETEROCYCLES WITH PALLADIUM(II) ACETATE AND SODIUM NITRITE.
Itahara,Ebihara,Kawasaki
, p. 2171 - 2172 (2007/10/02)
Treatments of 1,3-dimethyluracil, 1-methyl-2-pyridone, and thiophene with palladium(II) acetate and sodium nitrite gave the corresponding nitro-substituted products.
