21728-15-4 Usage
Uses
Used in Agricultural Industry:
4,7-Dichloro-2,8-dimethylquinoline is used as a pesticide for controlling a wide range of pests, including aphids, caterpillars, and mites. It serves as a crop protectant, ensuring the health and productivity of agricultural crops by preventing damage caused by these pests.
Used in Pharmaceutical Research:
4,7-Dichloro-2,8-dimethylquinoline is used as a research compound in the pharmaceutical industry due to its potential anti-tumor and anti-inflammatory properties. Its unique chemical structure and biological activities make it a promising candidate for the development of new drugs targeting various diseases.
However, it is important to note that 4,7-dichloro-2,8-dimethylquinoline also poses potential health and environmental risks due to its toxicity and persistence in the environment. Therefore, its use in various applications should be carefully evaluated and managed to minimize any adverse effects.
Check Digit Verification of cas no
The CAS Registry Mumber 21728-15-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,7,2 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 21728-15:
(7*2)+(6*1)+(5*7)+(4*2)+(3*8)+(2*1)+(1*5)=94
94 % 10 = 4
So 21728-15-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H9Cl2N/c1-6-5-10(13)8-3-4-9(12)7(2)11(8)14-6/h3-5H,1-2H3
21728-15-4Relevant articles and documents
N1-{4-[(10S)-Dihydroartemisinin-10-oxyl]}phenylmethylene-N 2-(2-methylquinoline-4-yl)hydrazine derivatives as antiplasmodial falcipain-2 inhibitors
Luo, Wei,Liu, Yang,Wang, Jian,Guo, Chun,Lu, Wei-Qiang,Cui, Kun-Qiang
, p. 3073 - 3079,7 (2020/08/20)
A series of N1-{4-[(10S)-dihydroartemisinin- 10-oxyl]}phenylmethylene-N2-(2-methylquinoline-4-yl) hydrazine derivatives 9a-9n possessing 4-quinolylhydrazone and artemisinin cores were herein synthesized and evaluated for their activities against cysteine protease falcipain- 2 of Plasmodium falciparum. The structures were clearly confirmed by elemental analysis, 1H NMR, and mass spectra. The pharmacological results indicated that all compounds showed excellent activity against recombinant falcipain-2 (IC50 = 0.15-2.28 μM). The best one of this series was compound 9d (IC50 = 0.15 μM). The molecular docking results showed that the compound 9d made close contact with the key active site of cysteine protease falcipain-2.
