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CAS

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Okadaic Acid Potassium Salt is a naturally occurring compound derived from marine sponges and certain dinoflagellates. It is a potent protein phosphatase inhibitor, specifically targeting PP1, PP2A, PP2B, and PP2C. This characteristic makes it a valuable tool in the study of various cellular processes and biochemistry.

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  • 155751-72-7 Structure
  • Basic information

    1. Product Name: OKADAIC ACID POTASSIUM SALT
    2. Synonyms: HALOCHONDRINE A;HALOCHONDRINE A, POTASSIUM SALT;9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN, POTASSIUM SALT;9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIOFOLICIN;OKADAIC ACID POTASSIUM SALT;OKADAIC ACID POTASSIUM SALT, PROROCENTRUM CONCAVUM;OKADAIC ACID POTASSIUM;OKADAIC ACID POTASSIUM SALT 98%
    3. CAS NO:155751-72-7
    4. Molecular Formula: C44H67KO13
    5. Molecular Weight: 843.09
    6. EINECS: N/A
    7. Product Categories: Inhibitor
    8. Mol File: 155751-72-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: white/powder
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: −20°C
    8. Solubility: H2O: 0.1 mg/mL
    9. Water Solubility: Soluble in DMSO or ethanol. Soluble in water at 0.1mg/ml. Also soluble in methanol
    10. CAS DataBase Reference: OKADAIC ACID POTASSIUM SALT(CAS DataBase Reference)
    11. NIST Chemistry Reference: OKADAIC ACID POTASSIUM SALT(155751-72-7)
    12. EPA Substance Registry System: OKADAIC ACID POTASSIUM SALT(155751-72-7)
  • Safety Data

    1. Hazard Codes: T
    2. Statements: 23/24/25-38
    3. Safety Statements: 26-36/37/39-45
    4. RIDADR: UN 2811 6.1 / PGIII
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: 6.1
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 155751-72-7(Hazardous Substances Data)

155751-72-7 Usage

Uses

Used in Biochemical Research:
Okadaic Acid Potassium Salt is used as a response modifier for studying the biochemistry of large granular lymphocytes and T-cells. It plays a crucial role in understanding the complex interactions and signaling pathways within these cells.
Used in Tumor Promotion Studies:
As a tumor promoter, Okadaic Acid Potassium Salt is utilized to investigate the mechanisms behind tumor development and progression. It helps researchers understand how certain compounds can influence cellular transformation and contribute to cancer.
Used in Nitric Oxide Metabolism Research:
Okadaic Acid Potassium Salt is employed in the study of nitric oxide metabolism, a critical process in various physiological and pathological conditions. It aids in elucidating the role of protein phosphatases in regulating nitric oxide production and its subsequent effects on the body.
Used in Apoptosis Research:
OKADAIC ACID POTASSIUM SALT is used to study apoptosis, or programmed cell death, which is essential for maintaining cellular homeostasis and preventing the development of diseases such as cancer. Okadaic Acid Potassium Salt helps researchers explore the intricate balance between cell survival and cell death.
Used in Cell Cycle Research:
Okadaic Acid Potassium Salt is utilized in the study of the cell cycle, a series of events that lead to cell division and replication. It assists in understanding how protein phosphatases regulate the progression of the cell cycle and the checkpoints that ensure proper cell division.
Used in Calcium Signaling Research:
OKADAIC ACID POTASSIUM SALT is used to investigate calcium signaling, a vital process in cellular communication and function. Okadaic Acid Potassium Salt helps researchers examine the role of protein phosphatases in modulating calcium-dependent signaling pathways and their impact on cellular processes.

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

Check Digit Verification of cas no

The CAS Registry Mumber 155751-72-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,7,5 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 155751-72:
(8*1)+(7*5)+(6*5)+(5*7)+(4*5)+(3*1)+(2*7)+(1*2)=147
147 % 10 = 7
So 155751-72-7 is a valid CAS Registry Number.
InChI:InChI=1/C46H72O13.K/c1-27-20-35(56-46(22-27)36(48)12-15-42(7,59-46)24-43(8,52)40(50)51)28(2)10-14-41(6)17-18-45(58-41)16-11-34-39(57-45)37(49)30(4)38(55-34)33(47)21-29(3)32-23-44(26-54-31(32)5)13-9-19-53-25-44;/h10,14,22,28-29,31-39,47-49,52H,4,9,11-13,15-21,23-26H2,1-3,5-8H3,(H,50,51);/b14-10+;

155751-72-7 Well-known Company Product Price

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  • Sigma

  • (O7885)  Okadaic acid potassium salt from Prorocentrum concavum  ≥90% (HPLC), powder

  • 155751-72-7

  • O7885-10UG

  • 833.04CNY

  • Detail
  • Sigma

  • (O7885)  Okadaic acid potassium salt from Prorocentrum concavum  ≥90% (HPLC), powder

  • 155751-72-7

  • O7885-25UG

  • 1,687.14CNY

  • Detail
  • Sigma

  • (O7885)  Okadaic acid potassium salt from Prorocentrum concavum  ≥90% (HPLC), powder

  • 155751-72-7

  • O7885-50UG

  • 2,471.04CNY

  • Detail

155751-72-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name OKADAIC ACID POTASSIUM SALT

1.2 Other means of identification

Product number -
Other names 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN,POTASSIUM SALT

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:155751-72-7 SDS

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