119425-90-0Relevant articles and documents
Derivative of loureirin B as well as preparation method and application of derivative
-
, (2018/03/01)
The invention discloses a derivative of loureirin B as well as a preparation method and application of derivative. The derivative of the loureirin B has the structure shown in the description. According to the preparation method disclosed by the invention, the structure of the loureirin B is modified and transformed; the derivative produced by the design retains analgesic activity of the loureirin B; the structural stability of the derivative is far higher than that of the loureirin B; in addition, the activity of a voltage-gated potassium channel Kv1.3 for blocking autoimmune disease is also remarkably improved.